1. Bull World Health Organ. 1971;45(3):371-5. Significance of the chemotherapeutic index in the treatment of schistosomiasis with antimony compounds.
A number of antimony compounds have been used for the treatment of schistosomiasis e.g., sodium antimony tartrate, sodium antimony dimercaptosuccinate (stibocaptate, Astiban) sodium antimonyl ...
A number of antimony compounds have been used for the treatment of schistosomiasis e.g., sodium antimony tartrate, sodium antimony dimercaptosuccinate (stibocaptate, Astiban) sodium antimonyl
Effect of the antimony compounds, fuadin and tartar emetic, on the electrocardiogram of man; a study of the changes encountered in 141 patients treated for schistosomiasis. TARR L. Ann Intern Med, (6):970-988 1947 MED: 18919994
Trivalent and pentavalent antimony compounds have been used for the treatment of parasitic diseases, particularly leishmaniasis and schistosomiasis, for over 100 years. Although trivalent antimony in the form of potassium or sodium antimony tartrate was first used, it …
Ambulant treatment of urinary schistosomiasis with Astiban (TWSb/6). BARUFFA G. PMID: 13865538 [PubMed - indexed for MEDLINE] MeSH Terms. Antimony/therapy* Organometallic Compounds; Schistosomiasis/therapy* Schistosomiasis haematobia* Succimer* Urinary Tract Infections/therapy* Substances. Organometallic Compounds; Antimony; stibocaptate; Succimer
Two-hundred and one electrocardiograms recorded in 38 patients with schistosomiasis who received 42 courses of therapy with antimony dimercaptosuccinate are reviewed; special attention was directed toward the relationship of hepatic dysfunction to cardiac toxicity. Significant electrocardiographic changes, when they occurred, involved the T waves.
Normally, antimony is absorbed slowly when ingested or administered orally. Many antimony compounds are gastrointestinal irritants. The emetic antimony potassium tartrate is easily absorbed and, within 24 h, 50% is excreted in the urine (hamsters). Antimony can concentrate in lung tissue, the thyroid gland, the adrenal glands, the kidneys, and ...
Antimony* Iraq Lucanthone* Organometallic Compounds Schistosomiasis haematobia* Schistosomiasis* Succimer* Urinary Tract Infections* Substances Organometallic Compounds Antimony ...
Antimony sulfide (stibnite) was ground into a powder called kohl which could then be used as an eye cosmetic. Is antimony still used in medicine? Today, neither metallic antimony nor its compounds have a medical use, although up to the 1970s, antimony compounds were used to treat parasitic infections like schistosomiasis.
Treatment of schistosomiasis mansoni with antimony lithium thiomalate (Anthiomaline); final report. RODRIGUEZ-MOLINA R, ACEVEDO CE, TORRES JM, LOPEZ-SANABRIA U, RAMIREZ-RODRIGUEZ E. PMID: 14790178 [PubMed - indexed for MEDLINE] MeSH Terms. Antimony* Lithium* Organometallic Compounds* Schistosomiasis* Schistosomiasis mansoni* Thiomalates* Substances
Organometallic Compounds* Schistosoma* Schistosomiasis* Substances Benzenesulfonates Emetics Organometallic Compounds Stibophen Antimony ... Antimony Antimony Potassium Tartrate ...
Rashad S. Barsoum, in Comprehensive Clinical Nephrology (Fourth Edition), 2010 Schistosoma haematobium Urinary Tract Disease. S. haematobium is susceptible to antimony compounds, organophosphates (metrifonate), and niridazole, but the current drug of choice is praziquantel, the most effective and least toxic. It is administered as a single oral dose of 40 mg/kg body weight.
Effect of the Antimony Compounds, Fuadin and Tartar Emetic, on the Electrocardiogram of Man ; a Study of the Changes encountered in 141 Patients treated for Schistosomiasis. Author(s) : Tarr, L. Journal article : Ann. Intern. Med. 1947 Vol.27 No.6 pp.970-88 ref.5 figs. 13
Observations on the treatment of schistosomiasis mansoni with antimony dimercaptosuccinate (TWSb) Am J Med. 1963 Apr;34:477-82. doi: 10.1016/0002-9343(63)90070-6.
There are three antimony compounds most commonly used in the treatment of schistosomiasis and all are trivalent: Tartar emetic (sodium and potassium tartrate). A freshly made 0.5 per cent solution is given intravenously in doses of 5, 10, and 15 c.c. on the first, third, and fifth days, and subsequently 20 c.c. every other day until a total of ...
Treatment of urinary bilharziasis with antimony dimercaptosuccinate (TWSb). ALVES W. PMID: 13511426 [Indexed for MEDLINE] MeSH terms. Antimony/therapeutic use* Humans; Organometallic Compounds; Schistosomiasis/therapy* Schistosomiasis haematobia* Succimer* Succinates/therapeutic use* Urologic Diseases* Substances. Organometallic Compounds ...
europe pmc is an archive of life sciences journal literature. chemotherapy of experimental schistosomiasis mansoni: influence of dimercaptosuccinic acid on the toxicity and antischistosomal activity of sodium antimony dimercaptosuccinate and other antimony compounds in mice.
Antimony/therapy* Humans; Organometallic Compounds; Schistosomiasis/therapy* Schistosomiasis haematobia* Somalia; Succimer* Urinary Tract Infections/therapy* Substances. Organometallic Compounds; Antimony; stibocaptate; Succimer
George A. Conder, in Antibiotic and Chemotherapy (Ninth Edition), 2010 Other anthelmintic agents. Potassium antimony tartrate (tartar emetic), sodium antimony tartrate, the thioxanthone, hycanthone, and the 5-nitrothiazole, niridazole, were formerly used in the treatment of schistosomiasis, but have been largely superseded by less toxic compounds. . Niridazole has also been used in Guinea worm ...
Potassium antimony tartrate (tartar emetic), sodium antimony tartrate, the thioxanthone, hycanthone, and the 5-nitrothiazole, niridazole, were formerly used in the treatment of schistosomiasis, but have been largely superseded by less toxic compounds. Niridazole has also been used in Guinea worm infection, but no drug interrupts transmission ...
1. J Egypt Med Assoc. 1960;43:696-707. Treatment of schistosomiasis, past & present. III. Synergism between antimony (tartar emetic). & thioxanthone compounds in the treatment of schistosomiasis.
Many of the antimony's compounds are toxic. Compounds of trivalent antimony are more toxic, than compounds of pentavalent antimony. ... (for instance schistosomiasis). In a word, antimony – one of the most ancient metals, known to mankind, and it is still essential for …
The Lancet ORIGINAL ARTICLES SCHISTOSOMIASIS INTENSIVE TREATMENT WITH ANTIMONY William Alves B.A. DysonM. Blair O.B.E., M.B. Edin., D.P.H. From the Schistosomiasis Research Laboratory, Salisbury, Southern Rhodesia A PRELIMINARY note on the intensive treatment of 6 cases of schistosomiasis with antimony has already been published (Alves 1945) ; in this paper a further …
For chemical compounds containing antimony.For an alternative listing please see inorganic_compounds_by_element#Antimony.. Subcategories. This category has the following 3 subcategories, out of 3 total.
DAVIS A. The effect of antimony dimercapto-succinate on the electrocardiogram. Br Heart J. 1961 May; 23:291–296. [Europe PMC free article] [Google Scholar] FAIRLEY NH. Schistosomiasis and some of its problems. Trans R Soc Trop Med Hyg. 1951 Dec; 45 (3):279–306. [Google Scholar] FORSYTH DM, …
trypenoBoraiasis, leishmaniasis, schistosomiasis, granuloma venereum, bilh-^rziosis, beri-beri, and syphilis. In the case of schistosomiasis, antimony compounds have proved so success ful that they are noiv regarded as specifics for the disease. The use of water-soluble organoantimony compounds holds much promise in therapy.
Jan 21, 1998· Antimony compounds are soluble in very strong acid and basic solutions. Under neutral conditions, the predominant species is Sb(OH) 6-for pentavalent forms and Sb(OH) 3. for trivalent forms. Some notable antimony compounds are diantimony xide (Sb. 2. O. 3, also called antimony xide), which is slightly soluble in water (2.76 mg/L), and ...
Originally the most successful drugs in treatment of schistosomiasis contained antimony and included tartar emetic, Fuadin and others. More recently non-metallic compounds such as Miracil and a series of diaminodiphenoxyalkanes have been used with some success. During screening procedures [this Bulletin, 1955, v. 52, 177] for schistosomicidal substances in mice it was found that complexes of...
Antimony Compounds in Infestation by Schistosoma mansoni. ... author gives more than 250 references to the literature of this subject from writers in all parts of the world where schistosomiasis exists, evidence that he has made a very thorough study of the question, and this thesis will probably hold for many years-until, indeed, more ...
Antimony potassium tartrate, also known as potassium antimonyl tartrate, potassium antimontarterate, or emetic tartar, has the formula K 2 Sb 2 (C 4 H 2 O 6) 2. The compound has long been known as a powerful emetic, and was used in the treatment of schistosomiasis and leishmaniasis. It is …
Apr 03, 2020· Today, neither metallic antimony nor its compounds have a medical use, although up to the 1970s, antimony compounds were used to treat parasitic infections like schistosomiasis. Does antimony break easily? Antimony breaks easily, but when mixed into alloys, it is used in lead storage batteries, solder, sheet and pipe metal, bearings, castings ...
The antimony compounds have main pharmacological use in the treatment of the parasitic diseases, leishmaniasis, and schistosomiasis. In 1631, the compound of antimony, potassium antimony tartrate, has been introduced by the German alchemist, Adrian Von Mynsicht; however, after that, the antimony compounds lost their value due to their toxic
The antimony compounds have main pharmacological use in the treatment of the parasitic diseases, leishmaniasis, and schistosomiasis. In 1631, the compound of antimony, potassium antimony tartrate, has been introduced by the German alchemist, Adrian Von Mynsicht; however, after that, the antimony compounds lost their value due to their toxic ...
Arsenic and antimony compounds are used to treat endemic diseases, such as cancer, leishmaniasis, and schistosomiasis, in spite of their toxicity. Several studies seeking the development and characterization of nanocarrier systems such as liposomes are being carried out with the aim of developing ne …
Electrocardiographic changes occuring with trivalent antimony compounds during therapy of schistosomiasis. ... Electrocardiographic changes occuring with trivalent antimony compounds during therapy of schistosomiasis. LAU FY. California Medicine, 01 Aug 1953, 79(2): 114-117 PMID: 13067028 PMCID: PMC1522005 ...